Zeta Surgical

Zeta Surgical is a Boston-based medical technology company developing advanced surgical navigation and robotics tools. Founded in 2018 by Harvard University graduates Jose Amich and Raahil Sha, along with Harvard Medical School professor and neurosurgeon Dr. William Gormley, the company aims to make minimally invasive surgeries easier, faster, and more accessible. Amich, the CEO, and Sha, the CTO, were recognized on the Forbes 30 Under 30 list in 2024 for their work.

The company's core product is the Zeta Cranial Navigation System, a platform that uses computer vision, artificial intelligence, and mixed reality to provide surgeons with real-time, "GPS-like" guidance for cranial procedures. The system has sub-millimeter accuracy and is designed for rapid deployment, taking less than five minutes to set up. A key feature is its ability to track patient and instrument movement in real-time without the need for rigid head fixation, allowing for procedures to be performed on awake patients outside of traditional operating rooms, such as in ICUs and emergency rooms. This addresses a major obstacle in point-of-care neurosurgery.

Zeta Surgical's technology received its first 510(k) clearance from the U.S. Food and Drug Administration (FDA) in September 2023, with subsequent clearances in 2024 expanding its instrument compatibility and software features. The company has completed successful clinical trials for ventriculostomy procedures in Singapore at Singapore General Hospital and Tan Tock Seng Hospital, demonstrating high accuracy and safety. The company's business model involves selling its FDA-cleared navigation system, with plans to launch commercial pilots in the U.S. The system is also being developed to support a non-invasive focused ultrasound system (ZetaFUS) for intracranial drug delivery.

Zeta Surgical has raised approximately $8.16 million in seed funding from investors including Y Combinator, Innospark Ventures, and TSVC. The firm is partnered with design consultancy Design + Industry and has received multiple design and innovation awards.

Keywords: surgical navigation, neuronavigation, medical robotics, computer-assisted surgery, mixed reality surgery, artificial intelligence in surgery, neurosurgery technology, cranial navigation, image-guided surgery, point-of-care surgery, minimally invasive neurosurgery, digital surgery, focused ultrasound, Zeta Cranial Navigation System, ventriculostomy, brain biopsy guidance, surgical robotics platform, medical device, FDA 510(k) clearance, neurotechnology