Vitro3D

Vitro3D, which rebranded to Manifest Technologies in April 2025, is an additive manufacturing firm that originated as a spin-out from the University of Colorado Boulder in 2020. The company was established by Dr. Camila Uzcategui (CEO) and Johnny Hergert (CTO), who began their collaboration as PhD students. Dr. Uzcategui's background in material science and a desire to improve global healthcare access to medical devices fueled the venture's direction.

The company is developing a volumetric 3D printing technology, termed Parallax Volumetric Additive Manufacturing (P-VAM), previously known as High Dimensionality Volumetric Additive Manufacturing (HD-VAM). This process solidifies objects from a volume of photosensitive resin simultaneously, rather than building them layer-by-layer. The core of the technology relies on a proprietary algorithm, specialized hardware, and materials science to project controlled light from multiple angles, curing the resin into a complete part in seconds. This method is reported to be significantly faster than conventional 3D printing techniques, can handle highly viscous resins, and reduces or eliminates the need for support structures and extensive post-processing.

The business model appears to involve the sale or lease of its proprietary printers, such as the Vitro3D Volumetric Cartridge Printer, and providing software-based solutions. The company emphasizes an open resin system, allowing customers to use their own certified materials. Vitro3D is targeting several markets, with an initial focus on producing dental aligners directly in-office for dentists. Further applications include creating scaffolds for tissue engineering and 3D cell culture for the pharmaceutical drug discovery process. The technology's potential also extends to the electronics industry, where it could be used to encase components.

A significant milestone was achieved in November 2022, when the company secured $1.3 million in a seed funding round led by Buff Gold Ventures, with participation from Rockies Venture Club, Caruso Ventures, and The Deming Center Venture Fund. This capital is being used to produce prototype printers. In April 2025, alongside its rebranding, the company launched its first P-VAM evaluation kit to allow engineering teams and researchers to test the technology.

Keywords: Volumetric Additive Manufacturing, Parallax Volumetric Additive Manufacturing, P-VAM, photopolymer resin, 3D printing, medical devices, dental aligners, tissue engineering, 3D cell culture, drug discovery, scaffold manufacturing, rapid prototyping, additive manufacturing hardware, materials science, Camila Uzcategui, Johnny Hergert, University of Colorado Boulder, Manifest Technologies, cartridge-based printing, support-free 3D printing, high-viscosity resin printing