The Art of Discovery

The Art of Discovery SL (TAD) is a preclinical contract research organization (CRO) based in the Basque Country of Spain, specializing in drug evaluation for biotech and pharmaceutical companies. The company reports over 20 years of continuous operation, positioning itself as a partner in drug discovery and development to de-risk and accelerate timelines for bringing treatments to the clinic.

The core of TAD's service offering revolves around its proprietary humanized mouse model, TADhuMouse®, and its mathematical analysis and prediction models, TADmaps®. This integrated platform is designed to translate data from mouse studies to inform human therapy, offering a new standard in preclinical and clinical evaluation. The company provides these services to a global client base, including leading research institutions and companies across various countries and continents. TAD's primary areas of focus include malaria, hematotoxicity, and cancer. The business model is service-based, providing flexible in vivo support for research projects, which can range from single-drug evaluations to constructing dedicated facilities and research teams for longer-term collaborations.

The company's offerings are aimed at addressing critical needs in the drug discovery pipeline, such as evaluating new antimalarial medicines for use in developing countries. TAD's work involves transplanting humanized mice with human blood to test the efficacy of new drugs. One of the founders appears to be Álvaro Ceballos, a philologist and writer from Madrid with a Ph.D. from the University of Göttingen, who has been a professor of Spanish literature at the University of Liège since 2008. Another individual associated with similar research in Spain is Sira Mogas-Díez, who holds a Ph.D. in Biomedicine from Universitat Pompeu Fabra (UPF) and is the founder of KOA Biotech, a spin-off from UPF focused on aquaculture technology. Mogas-Díez's research has involved developing cellular devices printed on paper for diagnostic applications, such as detecting mercury.

Keywords: preclinical CRO, drug discovery, drug development, humanized mouse models, translational science, in vivo services, pharmaceutical services, biotechnology, malaria research, hematotoxicity, cancer research, drug evaluation, TADhuMouse, TADmaps, biopharmaceutical development, preclinical trials, toxicology studies, pharmacology services, biomedical research, drug efficacy testing