ReaMetrix

ReaMetrix, founded in 2003 by the seasoned Silicon Valley entrepreneur Dr. Bala S. Manian, operated in the biotechnology sector with a focus on in-vitro diagnostic platforms. Dr. Manian, a prolific inventor with a Ph.D. from Purdue and a background in optics, has founded a series of successful medical technology companies, including Quantum Dot Corporation and Lumisys, leveraging his extensive experience in electro-optical systems. ReaMetrix was established with a vision to provide high-quality, affordable diagnostic solutions, particularly for resource-limited settings, with facilities in San Carlos, California, and Bangalore, India.

The company's core business involved developing and commercializing diagnostic platforms and providing related services to the pharmaceutical, biotechnology, and diagnostic industries. ReaMetrix offered GMP-level assay development, validation, testing services, and custom reagent labeling. A key product was its flagship instrument, IMMEDIA, a fluorescence measurement-based device designed for multiple sample types and assay formats. The company made significant strides in HIV management with its 'Dry Tri-T Stat' product, a temperature-stable, dried-down CD4 enumeration product for flow cytometry that received USFDA clearance. This format eliminated the need for refrigeration and was considerably more affordable than existing alternatives.

Financially, ReaMetrix raised a total of $10.9 million over four funding rounds from investors including Sequoia Capital, WestBridge Capital, and Baring Private Equity Partners. The company's journey culminated in August 2013 when the flow cytometry business assets of its Indian subsidiary, ReaMetrix India Pvt. Ltd., were acquired by Beckman Coulter Life Sciences. This acquisition provided Beckman Coulter with ReaMetrix's temperature-stable antibody cocktails, aiming to simplify sample preparation workflows for cytometry laboratories globally, especially in HIV monitoring and clinical research. Following this transaction, ReaMetrix is now considered a deadpooled company.

Keywords: in-vitro diagnostics, flow cytometry, biotechnology services, assay development, diagnostic platforms, GMP validation, HIV management, CD4 enumeration, reagent kits, Bala S. Manian, Beckman Coulter Life Sciences, Sequoia Capital, temperature-stable reagents, clinical research, life science technology, molecular diagnostics, fluorescence measurement, custom labeling, immunoassay