NLT SPINE

NLT Spine, founded in 2006 by Dr. Tzony Siegal, emerged from the Incentive incubator in Ariel, Israel, as a medical device company focused on developing solutions for minimally invasive spine surgery (MISS). The company was established based on Dr. Siegal's research into non-linear technology, which enables the insertion of large instruments and implants through very small incisions. A significant milestone was achieved in August 2016 when SeaSpine Holdings Corporation acquired NLT Spine's assets in a deal potentially valued up to $52.5 million, marking SeaSpine's first strategic acquisition as a standalone company.

The company's business was centered on designing, developing, and marketing instruments and implants for treating degenerative spinal conditions, particularly for lumbar fusion procedures. Its target clients were spine surgeons and medical facilities performing these specialized surgeries. The business model involved direct sales of its proprietary medical devices. The core of its product offering was a patented non-linear technology platform. This allowed instruments and implants to be inserted in a straight, low-profile form and then deploy into a larger, pre-defined curved shape once in the correct position within the body. This approach aimed to reduce tissue disruption and shorten operative times compared to traditional open surgery.

Key products included the PROW FUSION™ and PROW FUSION-V™ interbody fusion devices for Transforaminal Lumbar Interbody Fusion (TLIF) procedures. These implants featured a segmented, non-linear structure designed to create a large footprint for stability and bone graft contact. Another notable product was the eSPIN™ powered discectomy system, an instrument for cutting and grinding intervertebral disc material during fusion procedures. Both the PROW FUSION and eSPIN systems received 510(k) clearance from the U.S. Food and Drug Administration (FDA), as well as CE Marks for use in Europe, paving the way for their commercialization. Before its acquisition, Didier Toubia served as the company's CEO, bringing extensive experience from the medical device industry, having previously co-founded and led IceCure Medical.

Keywords: minimally invasive spine surgery, MISS, non-linear technology, spinal implants, interbody fusion, lumbar fusion, transforaminal lumbar interbody fusion, TLIF, discectomy, medical device, spine surgery instruments, Prow Fusion, eSpin, SeaSpine, Tzony Siegal, Didier Toubia, degenerative disc disease, spinal stenosis, expandable implants, medtech, orthopedic surgery