NeoProteomics

NeoProteomics operates as a contract research organization focused on structural biology and mass spectrometry. Founded in 2006 by Dr. Mark Chance, John L. H. Schenkel, Jr., and Steven Chance, the company is headquartered in the Cleveland, Ohio area. It was established to evaluate and commercialize technologies developed at the Center for Proteomics and Bioinformatics at Case Western Reserve University (CWRU), where Dr. Chance serves as Director. This origin provides NeoProteomics with a licensed intellectual property portfolio from CWRU, which forms the basis of its service offerings.

The company's business is centered on providing advanced research services and analytical tools to pharmaceutical companies, biotech firms, and research laboratories worldwide. Its primary service utilizes a proprietary covalent labeling technology, also known as protein footprinting, to characterize protein-protein or protein-ligand interactions. This technique, specifically using hydroxyl radical protein footprinting, helps researchers identify the binding sites of molecules, which is a critical step in drug discovery and development. NeoProteomics offers services including epitope and paratope mapping, structural analysis, and support for crystallography studies, all designed to increase the speed and accuracy of developing biologics and small molecule drugs.

The leadership team's background is rooted in both science and business. Dr. Mark R. Chance, the Chief Scientific Officer, is also the Vice Dean for Research at Case Western Reserve University, providing deep scientific direction. John L. H. Schenkel, Jr., the President and CEO, brings over 25 years of experience in business development, marketing, and management to oversee the company's daily operations and strategic direction. The company has received funding through grants, including a notable one from the HHS in 2011, and support from organizations like BioEnterprise and Innovation Fund America.

Keywords: proteomics, mass spectrometry, structural biology, contract research, drug discovery, protein footprinting, covalent labeling, epitope mapping, biologics development, small molecule drugs, protein analysis, pharmaceutical services, biotech research, Case Western Reserve University, protein-ligand interaction, structural analysis, protein characterization, drug development services, hydroxyl radical protein footprinting, research tools