Lexogen

Lexogen GmbH, a Vienna-based biotechnology firm, was established in August 2007 by Alexander Seitz, MD. The company's inception was supported by the INiTS business incubator and received seed financing from Austria Wirtschaftsservice (aws), the Austrian federal promotional bank. Dr. Seitz, who received his M.D. from the University of Innsbruck, has a background in molecular biology and regenerative medicine, including postdoctoral work in the US and independent research in Germany, where he developed and patented a new method for analyzing gene expression. This expertise in RNA became the foundation of Lexogen. In August 2020, Dr. Seitz transitioned to the role of Chief Innovation Officer, with Stéphane Barges appointed as the new CEO.

Lexogen operates in the transcriptomics and Next-Generation Sequencing (NGS) market, providing specialized tools for RNA analysis. The company's business model centers on the development, manufacturing, and sale of proprietary library preparation kits for RNA sequencing, as well as offering end-to-end NGS services. Its client base includes academic institutions, researchers, and pharmaceutical and biotech companies worldwide. Revenue is generated through the sale of these kits and sequencing services. To better serve its growing US customer base, a subsidiary, Lexogen, Inc., was established in New Hampshire in April 2014 as a distribution center.

The company's product portfolio is designed to analyze the complete transcriptome. Key products include the QuantSeq kits for 3' mRNA-Seq gene expression profiling, CORALL for whole transcriptome sequencing, and LUTHOR for single-cell RNA sequencing. These kits are complemented by solutions for every step of the RNA sequencing workflow, from RNA isolation and depletion with products like RiboCop and TraPR, to bioinformatics software for data analysis. Lexogen's proprietary technologies aim to provide highly strand-specific and sensitive results, even from low-quality or low-input samples such as FFPE tissue and blood. The company also provides fully customizable NGS services, covering experimental design, sequencing, and bioinformatics for various applications including DNA-Seq and multi-omic approaches.

Keywords: RNA sequencing, transcriptomics, Next-Generation Sequencing, gene expression profiling, library preparation kits, molecular biology, RNA analysis, bioinformatics, single-cell sequencing, Alexander Seitz, Vienna biotech, QuantSeq, CORALL, RiboCop, NGS services, mRNA-Seq, RNA isolation, transcriptome analysis, FFPE samples, blood transcriptomics