Diagenode

Diagenode S.A. operates as a specialized life sciences company, focusing on the development and sale of innovative systems for epigenetics research and molecular diagnostics. Founded in 2003 by Didier Allaer in Liège, Belgium, the company has established itself as a key provider of comprehensive solutions for researchers and clinicians. Didier Allaer, a mechanical engineer with a background in molecular biology, spent over 15 years at the biotech company Eurogentec before launching Diagenode, driven by a desire to explore new ventures in the field.

The company's business is segmented into two primary markets: epigenetics research and molecular diagnostics. For the research market, Diagenode supplies a wide array of products designed to streamline complex workflows like Chromatin Immunoprecipitation (ChIP), ChIP-seq, and DNA methylation analysis. Key products include the Bioruptor® series for DNA and chromatin shearing and the IP-Star® Automated System, which automates epigenetics assays. The product portfolio encompasses instruments, reagent kits, and highly validated antibodies, catering to life science researchers in academic, governmental, and biopharmaceutical sectors. Revenue is generated through the direct sale of these products and through providing specialized services, such as epigenomics profiling and data analysis.

In the diagnostics sector, Diagenode develops and manufactures CE-marked real-time PCR (polymerase chain reaction) tests. Its offerings include over 30 assays for detecting a range of pathogens, including bacteria, parasites, and viruses associated with infectious diseases like STIs, respiratory illnesses, and gastroenteritis. A significant milestone in the company's history was its acquisition by Hologic, Inc. in March 2021 for approximately $159 million. This event was a culmination of a partnership that began in 2016, where Diagenode assisted Hologic in developing and manufacturing PCR-based assays. The acquisition was intended to expand Hologic's molecular diagnostics business, enhance its international presence, and broaden its test menu.

Keywords: epigenetics, molecular diagnostics, chromatin immunoprecipitation, DNA methylation, life sciences, PCR tests, sample preparation, DNA shearing, Bioruptor, IP-Star, antibody development, ChIP-seq, infectious disease testing, genomics research, biomarker discovery, next-generation sequencing, automation instruments, laboratory services, Hologic, Didier Allaer, diagnostics assays