Aravis BioTech

Aravis BioTech

Implantable medical devices with sensors for fracture healing.

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Greenville, United States
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Aravis BioTech, founded in 2015, is developing implanted medical devices equipped with sensors to quantitatively track fracture healing and monitor for infection. The company's core technology aims to provide clinicians with objective data to assess bone healing, supplementing traditional X-rays which can be subjective and imprecise. This allows for more informed decisions regarding patient care, such as when it is safe to begin bearing weight on a fracture, potentially leading to faster rehabilitation and reduced complications.

The company was co-founded by a multidisciplinary team with backgrounds in chemistry, bioengineering, and orthopedic surgery. The founding team includes Jeffrey N. Anker, PhD, who serves as CEO; John DesJardins, PhD, the company's CTO; and Caleb Behrend, MD, the Chief Medical Officer. Anker is a professor of Chemistry and BioEngineering at Clemson University, while DesJardins is a professor in the Department of Bioengineering at Clemson. Dr. Behrend is a practicing orthopedic spine surgeon. Their collaboration began in 2010 and evolved through various research grants from institutions like the NIH to develop sensor-based medical implants.

Aravis BioTech's initial products include load-sensing screws, such as a sliding hip screw (LS-SHS), that contain a radio-dense indicator rod. The movement of this rod, visible on plain radiographs, corresponds to the load on the implant, providing a quantitative measure of healing. The company is also expanding this sensor technology to other orthopedic hardware like plates and developing sensors that can detect chemical changes associated with infection. By providing a clearer, data-driven picture of the healing process, Aravis BioTech aims to reduce medical costs and liabilities associated with suboptimal surgical outcomes. The company has received funding from sources including the South Carolina Research Authority (SCRA) and Parvizi Surgical Innovation.

Keywords: orthopedic implants, fracture healing, medical device sensors, implantable sensors, load-sensing screws, musculoskeletal diseases, quantitative healing assessment, orthopedic surgery, bioengineering, medical technology, infection biomarkers, sliding hip screw, bone regeneration, post-operative monitoring, clinical decision support, orthopedic hardware, trauma devices, medtech, therapeutic devices, surgical implants

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